SW8980308_Current Permit_20090731

HCDENA,
North Carolina Department of Environment and Natural Resources
Division of Water Quality
Beverly Eaves Perdue Coleen H. Sullins Dee Freeman
Govemor Director Secretary
July 31, 2009
Mr. Louis Karras, CEO
AAIPharma Services Corp.
2320 Scientific Park Drive
Wilmington, NC 28405
Subject: State Stormwater Management Permit No. SW8 980308
Applied Analytical Office Building Expansion
High Density Commercial Wet Detention Pond Project
New Hanover County
Dear Mr. Karras:
The Wilmington Regional Office received a complete Stormwater Permit Transfer of
Ownership Application for Applied Analytical Office Building Expansion on July 17,
2009. As required by the Stormwater Regulations set forth in Title 15A NCAC 2H.1000
effective September 1, 1995, this site was inspected on July 29, 2009 and found to be in
compliance with permit conditions. Therefore, permit SW8 980308 was transferred on
July 31, 2009 and shall be effective until April 30, 2018.
Please pay special attention to the Operation and Maintenance requirements in this
permit. Failure to establish an adequate system for operation and maintenance of the
stormwater management system will result in future compliance problems. The plans
previously approved on April 30, 1998 remain in full force and effect.
If any parts, requirements, or limitations contained in this permit are unacceptable, you
have the right to request an adjudicatory hearing upon written request within thirty (30)
days following receipt of this permit. This request must be in the form of a written
petition, conforming to Chapter 150B of the North Carolina General Statutes, and filed
with the Office of Administrative Hearings, P.O. Drawer 27447, Raleigh, NC 27611-
7447. Unless such demands are made this permit shall be final and binding.
If you have any questions, or need additional information concerning this matter, please
contact either Angela Hammers or me at [phone].
Sincerely,
Georgette Scott
Stormwater Supervisor
Division of Water Quality
GDS/akh: S:IWQSISTORMWATERIPERMIT1980308.jui09
cc: WiRO; Central Files; Angela Hammers
Wilmington Regional office
127 Cardinal Drive Extension, Wilmington, North Carolina 28405 One
Phone: 9I O-796 72151 FAX: [phone] Customer Service:1-877-623-6748 North Carolina
Internet vvww.ncwaterquallty.org �,. �}� y
An Equal Oppodudl I Affirmative Action ErrioWr �/ / mLNd4

State Stormwater Management Systems
Permit No. SW8 980308
STATE OF NORTH CAROLINA
DEPARTMENT OF ENVIRONMENT AND NATURAL RESOURCES
DIVISION OF WATER QUALITY
STATE STORMWATER MANAGEMENT PERMIT
HIGH DENSITY COMMERCIAL DEVELOPMENT
In accordance with the provisions of Article 21 of Chapter 143, General Statutes of
North Carolina as amended, and other applicable Laws, Rules, and Regulations
PERMISSION IS HEREBY GRANTED TO
Mr. Louis Karras & AA1Pharma Services Corp.
Applied Analytical Office Building Expansion
1206 N. 23'd Street, Wilmington, New Hanover County
FOR THE
construction, operation and maintenance of one wet detention pond(s) in compliance
with the provisions of 15A NCAC 2H .1000 effective September 1, 1995 (hereafter
referred to as the "stormwater rules') and the approved stormwater management plans
and specifications and other supporting data as attached and on file with and approved
by the Division of Water Quality and considered a part of this permit.
This permit shall be effective from the date of issuance until April 30, 2018, and shall be
subject to the following specified conditions and limitations:
I. DESIGN STANDARDS
1. This permit is effective only with respect to the nature and volume of stormwater
described in the application and other supporting data.
2. This stormwater system has been approved for the management of stormwater
runoff as described in Section 1.7 on page 3 of this permit. The stormwater
control has been designed to handle the runoff from 411,842 square feet of
impervious area.
3. The tract will be limited to the amount of built -upon area indicated on page 3 of
this permit, and per approved plans. The built -upon area for the future
development is limited to 0 square feet.
4. All stormwater collection and treatment systems must be located in either
dedicated common areas or recorded easements. The final plats for the project
will be recorded showing all such required easements, in accordance with the
approved plans.
5- The runoff from all built -upon area within the permitted drainage area(s) of this
project must be directed into the permitted stormwater control system.
Page 2 of 5

State Stormwater Management Systems
Permit No. SW8 980308
CQ
The following design criteria have been provided in the wet detention pond and
must be maintained at design condition:
a. Drainage Area, Gres:
Onsite, ft�
Offsite, ft2:
b. Total Impervious Surfaces, ft2:
C. Design Storm, inches:
d. Average Pond Design Depth, feet:
e. TSS removal efficiency:
f. Permanent Pool Elevation, FMS,�:
g. Permanent Pool Surface Areg, ft
h. Permitted Storage Volume, ft :
i. Temporary Storage Elevation, FMSL:
J Controlling Orifice:
k. Fountain Horsepower, HP
M. Receiving Stream/River Basin:
n. Stream Index Number:
o. Classification of Water Body:
II. SCHEDULE OF COMPLIANCE
13.66
433,365
161,665
411,842
1
6.5
90%
11.5
25,262
38,501
12.9
2.5"O pipe
not permitted
Smith Creek / Cape Fear
18-74-63
"C Sw"
1. The stormwater management system shall be constructed in its entirety,
vegetated and operational for its intended use prior to the construction of any
built -upon surface.
2. During construction, erosion shall be kept to a minimum and any eroded areas of
the system will be repaired immediately.
3. The permittee shall at all time provide the operation and maintenance necessary
to assure the permitted stormwater system functions at optimum efficiency. The
approved Operation and Maintenance Plan must be followed in its entirety and
maintenance must occur at the scheduled intervals including, but not limited to:
a. Semiannual scheduled inspections (every 6 months).
b. Sediment removal.
C. Mowing and re -vegetation of slopes and the'vegetated filter.
d. Immediate repair of eroded areas.
e. Maintenance of all slopes in accordance with approved plans and
specifications.
f. Debris removal and unclogging of outlet structure, orifice device,
flow spreader, catch basins and piping.
g. Access to the outlet structure must be available at all times.
4. Records of maintenance activities must be kept and made available upon
request to authorized personnel of DWQ. The records will indicate the date,
activity, name of person performing the work and what actions were taken.
5. Decorative spray fountains will be not be allowed in the stormwater treatment
system.
6. The facilities shall be constructed as shown on the approved plans. This permit
shall become void unless the facilities are constructed in accordance with the
conditions of this permit, the approved plans and specifications, and other
supporting data.
Page 3 of 5

State Stormwater Management Systems
Permit No. SW8 980308
7. Upon completion of construction, prior to issuance of a Certificate of Occupancy,
and prior to operation of this permitted facility, a certification must be received
from an appropriate designer for the system installed certifying that the permitted
facility has been installed in accordance with this permit, the approved plans and
specifications, and other supporting documentation. Any deviations from the
approved plans and specifications must be noted on the Certification. A
modification may be required for those deviations.
8. If the stormwater system was used as an Erosion Control device, it must be
restored to design condition prior to operation as a stormwater treatment device,
and prior to occupancy of the facility.
9. Access to the stormwater facilities for inspection and maintenance shall be
maintained via appropriate recorded easements at all times.
10. The permittee shall submit to the Director and shall have received approval for
revised plans, specifications, and calculations prior to construction, for any
modification to the approved plans, including, but not limited to, those listed
below:
a. Any revision to any item shown on the approved plans, including the
stormwater management measures, built -upon area, details, etc.
b. Project name change.
C. Transfer of ownership.
d. Redesign or addition to the approved amount of built -upon area or to the
drainage area.
e. Further development, subdivision, acquisition, lease or sale of any, all or
part of the project area. The project area is defined as all property owned
y the permittee, for which Sedimentation and Erosion Control Plan
approval or a CAMA Major permit was sought.
f. Filling in, altering, or piping of any vegetative conveyance shown on the
approved plan.
11. Prior to the construction of any permitted future areas shown on the approved
plans, the permittee shall submit final site layout and grading plans to the
Division for approval.
12. A copy of the approved plans and specifications shall be maintained on file by
the Permittee at all times.
13. The Director may notify the permittee when the permitted site does not meet one
or more of the minimum requirements of the permit. Within the time frame
specified in the notice, the permittee shall submit a written time schedule to the
Director for modifying the site to meet minimum requirements. The permittee
shall provide copies of revised plans and certification in writing to the Director
that the changes have been made.
III. GENERAL CONDITIONS
This permit is not transferable to any person or entity except after notice to and
approval by the Director. In the event of a change of ownership, or a name
change, the permittee must submit a completed Name/Ownership Change Form
signed by both parties, to the Division of Water Quality, accompanied by the
supporting documentation as listed on page 2 of the form. The approval of this
request will be considered on its merits and may or may not be approved.
2. The permittee is responsible for compliance with all permit conditions until such
time as the Division approves the transfer request. Neither the sale of the project
nor the transfer of common area to a third party constitutes an approved transfer
of the stormwater permit.
Page 4 of 5

State Stormwater Management Systems
Permit No. SW8 980308
3. Failure to abide by the conditions and limitations contained in this permit may
subject the Permittee to enforcement action by the Division of Water Quality, in
accordance with North Carolina General Statute 143-215.6A to 143-215.6C
effective September 1, 1995.
4. The issuance of this permit does not preclude the Permittee from complying with
any and all statutes, rules, regulations, or ordinances, which may be imposed by
other government agencies (local, state, and federal) having jurisdiction.
5. In the event that the facilities fail to perform satisfactorily, including the creation of
nuisance conditions, the Permittee shall take immediate corrective action,
including those as may be required by.this Division, such as the construction of
additional or replacement stormwater management systems.
6. The permittee grants DENR Staff permission to enter the property during normal
business hours for the purpose of inspecting all components of the permitted
stormwater management facility.
7. The permit remains in force and effect until modified, revoked, terminated or
renewed. The permit may be modified, revoked and reissued or terminated for
cause. The filing of a request for a permit modification, revocation and re -
issuance or termination does not stay any permit condition.
8. Unless specified elsewhere, permanent seeding requirements for the stormwater
control must follow the guidelines established in the North Carolina Erosion and
Sediment Control Planning and Design Manual.
9. Approved plans and specifications for this project are incorporated by reference
and are enforceable parts of the permit.
10. The permittee shall notify the Division of any name, ownership or mailing address
changes at least 30 days prior to making such changes.
11. The permittee shall submit a permit renewal request at least 180 days prior to the
expiration date of this permit. The renewal request must include the appropriate
documentation and the processing fee.
Permit issued this the 31St day of July 2009.
NORTH CAROLINA ENVIRONMENTAL MANAGEMENT COMMISSION
for coieen h. 5unms, uirector u
Division of Water Quality
By Authority of the Environmental Management Commission
Page 5 of 5

Permit Number:) �J 0 7 0 a3(}0V
(to be provided by DWQ)
Drainage Area Number:
Wet Detention Basin Operation and Maintenance Agreement
W-1
I will keep a maintenance record on this BMP. This maintenance record will be kept in a
log in a known set location. Any deficient BMP elements noted in the inspection will be
corrected, repaired or replaced immediately. These deficiencies can affect the integrity
of structures, safety of the public, and the removal efficiency of the BMP.
The wet detention basin system is defined as the wet detention basin,
pretreatment including forebays and the vegetated filter if one is provided.
This system (check one):
❑ does ® does not incorporate a vegetated filter at the outlet.
This system (check one):
❑ does ® does not incorporate pretreatment other than a forebay.
Important maintenance procedures:
- Immediately after the wet detention basin is established, the plants on the
vegetated shelf and perimeter of the basin should be watered twice weekly if
needed, until the plants become established (commonly six weeks).
- No portion of the wet detention pond should be fertilized after the first initial
fertilization that is required to establish the plants on the vegetated shelf.
- Stable groundcover should be maintained in the drainage area to reduce the
sediment load to the wet detention basin.
- If the basin must be drained for an emergency or to perform maintenance, the
flushing of sediment through the emergency drain should be minimized to the
maximum extent practical.
- Once a year, a dam safety expert should inspect the embankment.
After the wet detention pond is established, it should be inspected once a month and
within 24 hours after every storm event greater than 1.0 inches (or 1.5 inches if in a
Coastal County). Records of operation and maintenance should be kept in a known set
location and must be available upon request.
Inspection activities shall be performed as follows. Any problems that are found shall
be repaired immediately.
BMP element:
Potentialproblem:
How I will remediate theproblem:
The entire BMP
Trash debris is present
Remove the trash debris.
The perimeter of the wet
detention basin
Areas of bare soil and/or
erosive gullies have formed.
Regrade the soil if necessary to
remove the gully, and then plant a
ground cover and water until it is
established. Provide lime and a
one-time fertilizer application.
Vegetation is too short or tooj
Maintain vegetation at a height of
long,
approximately six inches.
Form SW401-Wet Detention Basin O&M-Rev.4 Page 1 of 4

BMP element:
The inlet device: pipe or
swale
The forebay
The vegetated
The main treatment area
Permit Number: 02(� 0 9 0 d,-3D51
(to be provided by DWQ)
Drainage Area Number:
Potential problem:
The pipe is clogged.
The pipe is cracked or
otherwise damaged.
Erosion is occurring in the
swale.
Sediment has accumulated to
a depth greater than the
original design depth for
sediment storage.
Erosion has occurred.
Weeds are present.
Best professional practices
show that pruning is needed
to maintain optimal plant
health.
Plants are dead, diseased or
dying.
Weeds are present.
Sediment has accumulated to
a depth greater than the
original design sediment
storage depth.
Algal growth covers over
50% of the area.
Cattails, phragmites or other
invasive plants cover 50% of
the basin surface.
How I will remediate the probl
Unclog the pipe. Dispose of the
sediment off -site.
Replace the pipe.
Regrade the swale if necessary to
smooth it over and provide erosion
control devices such as reinforced
turf matting or riprap to avoid
future problems with erosion.
Search for the source of the
sediment and remedy the problem if
possible. Remove the sediment and
dispose of it in a location where it
will not cause impacts to streams or
the BMP.
Provide additional erosion
protection such as reinforced turf
matting or riprap if needed to
prevent future erosion problems.
Remove the weeds, preferably by
hand. If pesticide is used, wipe it on
the plants rather than spraying.
Prune according to best professional
practices
Determine the source of the
problem: soils, hydrology, disease,
etc. Remedy the problem and
replace plants. Provide a one-time
fertilizer application to establish the
ground cover if a soil test indicates
it is necessary.
Remove the weeds, preferably by
hand. If pesticide is used, wipe it on
the plants rather than spraying.
Search for the source of the
sediment and remedy the problem if
possible. Remove the sediment and
dispose of it in a location where it
will not cause impacts to streams or
the BMP.
Consult a professional to remove
and control the algal growth.
Remove the plants by wiping them
with pesticide (do not spray).
Form SW401-Wet Detention Basin O&M-Rev.4 Page 2 of 4

Permit Number ji(J 0 9d i'S d D
(to be provided by DWQ)
Drainage Area Number:
BMP element:
Potentialproblem:
How I will remediate theproblem:
The embankment
Shrubs have started to grow
Remove shrubs immediately.
on the embankment.
Evidence of muskrat or
Use traps to remove muskrats and
beaver activity is present.
consult a professional to remove
beavers.
A tree has started to grow on
Consult a dam safety specialist to
the embankment
remove the tree.
An annual inspection by an
Make all needed repairs.
appropriate professional
shows that the embankment
needs repair. if applicable)
The outlet device
Clogging has occurred.
Clean out the outlet device. Dispose
of the sediment off -site.
The outlet device is damaged
Repair or replace the outlet device.
The receiving water
Erosion or other signs of
Contact the local NC Division of
damage have occurred at the
Water Quality Regional Office, or
outlet.
the 401 Oversight Unit at 919-733-
1756.
The measuring device used to determine the sediment elevation shall be such
that it will give an accurate depth reading and not readily penetrate into
accumulated sediments.
When the permanent pool depth reads 5.5 feet in the main pond, the sediment
shall be removed.
When the permanent pool depth reads 5.5 feet in the forebay, the sediment
shall be removed.
Sediment Removal
Bottom
6------------ 1]
FOREBAY
BASIN DIAGRAM
(fill in the blanks)
�ft Min.
Sediment
Storage
Permanent Pool Elevation 11.5
Pool
Sediment Removal Elevation 6 Volume
Bottom Elevation
MAINPOND
1-ft
Storage
Form SW401-Wet Detention Basin O&M-Rev.4 Page 3 of 4

Permit Number: S1 () OV,/O 3yY
(to be provided by DWQ)
I acknowledge and agree by my signature below that I am responsible for the
performance of the maintenance procedures listed above. I agree to notify DWQ of any
problems with the system or prior to any changes to the system or responsible party.
Project name:Applied Analytical Office Building Expansion
BMP drainage area number:
Print name:Louis Karras
Title:Senior Vice President of Pharmaceutical Services
Address:2320 Scientific Park Drive Wilmington, NC 28405
Date: /0 V
Note: The legally responsible party should not be a homeowners association unless more than 50% of
the lots have been sold and a resident of the subdivision has been named the president.
I, IZIa Notary Public for the State of
�� , Coun4 of 1Vec J A4o, , do hereby certify that
s &dzy_��-ems personally appeared before me this
day of �,r,�.� p� , ZOO N;" , and acknowledge the due execution of the
forgoing wet detention basin maintenance requirements. Witness my hand and official
SEAL
My commission expires
Form SW401-Wet Detention Basin O&M-Rev.4
Page 4 of 4

STATE OF NORTH CAROLINA
DEPARTMENT OF ENVIRONMENT AND NATURAL RESOURCES
DIVISION OF ENERGY, MINERAL AND LAND RESOURCES
STORMWATER MANAGEMENT PERMIT INFORMATION UPDATE FORM
This form is only to be used by the current permittee to: 1) change the Point of Contact (signing official) for
the current permittee (LLC, Corporation, HOA or POA); 2) change the mailing address, phone number or email
address of the current permittee; 3) changs the name of the project; and 4) change the legal corporate name
as documented by a Name Change filed with the NCSOS. For all transfers of the permit to a NEW OWNER
(including dissolution of the current permittee corporation or LLC and the transfer of assets to a new
corporation or LLC), please complete the "Permit Transfer Form".
I. CURRENT PERMIT INFORMATION
1. Stormwater Management Permit Number: SW8980308
2. Project Name: Applied Analytical Industries
3. Current / Previous Corporation Name: AAlPharma Services Corp.
4. Current Permit Holder's Company Name/Organization: AAlPharma services Corp.
5. Signing Official's Name: Marty Shelton Title: Senior Director, Operations Lab Support
Phone: [phone] Fax: �)
II. NEW PERMIT INFORMATION
Request the following information be updated: (Please check all that apply. If more than one point of contact or mailing
address is being changed, please attach a separate sheet.)
❑ Project Name - (Complete Item 1 below)
x❑ Corporation Name - (Complete Item 2 below and provide the Name Change filed with the NCSOS)
❑ Point of Contact (i.e., Signing Official, Property Owner, LLC Manager, HOA/POA president/manager) -
(Complete Items 3 & 4 below and provide a copy of supporting documentation such as-IVCSOS filing)
❑ Mailing Address / Phone Number/ Email Address - (Complete Item 5, 6, or 7 below, as applicable)
1. New Project Name:
2. New Corporation Name: Alcami Corporation
3. New Point of Contact Name: same as previous
4. New Point of Contact Title: Same as previous
5. New Mailing Address: Same as previous Apt./Suite#
City: State: Zip:
6. New Phone: Same as previous New Fax: �)
7. New Email Address: [e-mail] BV-
III. CURRENT PERMITTEE'S CERTIFICATION
Marty Shelton , the current permittee, hereby notify DEMLR that I am making the above
noted changes as listed in Section 11. 1 further attest that this application for an update to the permit information
currently on file is accurate and complete to the best of my knowledge.
Signature: � sgw ' Date: J.3-D ' - Zot 7
I, iC,� JlG� 1d1,6(,f , a Notary Public for the State of
County of (P,uJ 6(9fq p !/a-,/ , do hereby certify that
personally appeared before me this the day of g�&-ZZO IZIL , 20,ZZ, and acknow °0
due execution of the forgoing instrument. Witness my hand and official seal, J� )i
My commission expires L�iice Z Z
N ry Signature c n
ti AVBX 2
NN
9�oVER G©J

fA��
NCDENRNorth Carolina Department of Environment and Natural Resources
Division of Water Quality
STATE STORMWATER PERMIT NAMEIOWNERSHIP CHANGE FORM
I. CURRENT PERMIT INFORMATION:
1 Stormwater Management Permit Number: SW8 980308
2 Permit Holder's Name: AAIPharma
3 Signing official's Name: Al Cavaanaro Title: V. P. of Corporate Legal Services
(person legally responsible for permit)
4 Mailing Address: 2320 Scientific Park Drive City: Wilmington State: NC Zip: 28405
Phone: [phone] Fax: [phone]
H. NEW OWNER I PROJECT / ADDRESS INFORMATION:
1. This request is for: (please check all that apply)
X a. Change in ownership of the property/company (Please complete Items #2,
#3, and #4 below)
`b. Name change of project (Please complete Item #5 below)
c. Mailing address change. (Please complete Item #4 below)
d. Other (please explain):
2 New owner's name to be put on permit: AAIPharma Services Corp.
3 New owner's signing official's name and title: Lee Karras Title: CEO
4 New Mailing Address: Same City: State: Zip:
Phone:() Fax:( )
5 New Project Name to be placed on permit
Ownership/Name Change-022309 Page 1 of 3
PERMIT NAMEIOWNERSHIP CHANGE FORM
THIS APPLICATION PACKAGE WILL NOT BE ACCEPTED BY THE DIVISION OF WATER
QUALITY UNLESS ALL OF THE APPLICABLE ITEMS LISTED BELOW ARE INCLUDED WITH
THE SUBMITTAL.
REQUIRED ITEMS:
1 This completed form.
2 Legal documentation of the transfer of ownership.
3 A copy of the recorded deed restrictions, if required by the permit.
4 The designer's certification, if required by the permit.
5 A signed Operation and Maintenance plan, if a system that requires maintenance will
change ownership.
6 Maintenance records.

d
CERTIFICATION MUST BE COMPLETED AND SIGNED BY BOTH THE CURRENT PERMIT
HOLDER AND THE NEW APPLICANT IN THE CASE OF A CHANGE OF OWNERSHIP.
FOR NAME CHANGES, COMPLETE AND SIGN ONLY THE CURRENT PERMITTEE'S
CERTIFICATION.
Current Permittee's Certification:
I, Al Cava„ naro , attest that this application for a name/ownership change has been reviewed and
is accurate and complete to the best of my knowledge. I understand that if all required parts of this
application are not completed and that if all required supporting information and attachments are
not included, this application package will be returned as incomplete.
Signature:
New Applicant's Cer0cation: (Must be c ompWW for all transfers of ownership)
�6
I, Lee Karras , attest that this application for an ownership change has been reviewed and is
accurate and complete to the best of my knowledge. I understand that if all required parts of this
application are not completed and that if all required supporting information and attachments are
not included, this application packagp#ll be returned as incomplete.
Signatu
7/lk/0
Mail the entire package to: NCDENR Division of Water Quality
Surface Water Protection Section — Stormwater
at the Appropriate Contact Address (see the following page)
OwnershipMame Change-022308 Page 2 of 3 ownershildName Change-o2 M Page 3 of 3

mooN' p�
G7 f
O `C
op.,�?i� 970, SW 0g90903 0Y
Michael F. Easley, Governor
William G. Ross Jr., Secretary
North Carolina Department of Environment and Natural Resources
Alan W. Klimek, P.E. Director
Division of Water Quality
SURFACE WATER PROTECTION SECTION
COASTAL STORMWATER PERMIT RENEWAL APPLICATION FORM
I. CURRENT PERMIT INFORMATION: NKT #08143
1. Stormwater Management Permit Number: SW8 980308
2. Permit Holder's name:
(company, partnership, corporation, LLC, or individual)
3. Signing official's name: Louis Karras Title: Senior Vice President of Pharmaceutical Services
(person legally responsible for permit)
4. Mailing address: 2320 Scientific Park Drive City: Wilmington
State: NC ZipCode: 28405 Phone: [phone] FAX: [phone]
(Area Code and Number) (Area Code and Number)
5. Project Name: Applied Analytical Office Building Expansion
6. Location of Project: (street address) 1206 N. 23`d Street
7. Directions to Project (from nearest major intersection) Take Martin Luther King Parkway to 23rd St.
AAI is located at 1206 N. 23`d Street.
II. PERMIT INFORMATION
Specify the type of stormwater treatment (wet pond, infiltration, etc.): Wet Pond
2. List any changes (from project that was originally approved, attach additional pages if needed) N/A
3. Do you have a copy of the original Operation and Maintenance Agreement? ®Y ❑N
Applicant's Certification:
I, (print) Louis Karras, Senior Vice President of Pharmaceutical Services, certify that the
information included on this permit ewal application, is to the best of my knowledge, correct
and complete.
Signature: 11YA—Date: 12-1,fl v Jr
Submit this completed form along with an application fee of $505.00 and a copy of &mpa
designers certification to the address listed below. WY
North Carolina Division of Water Quality 127 Cardinal Drive Extension Wilmington, NC 28405 Phone [phone] Customer Service
Wilmington Regional Office Internet: www.ncwaMuality.org Fax [phone]

-- Andrew & Kuske
_ = = CONSULTING ENGINEERS, INC.
902 Market St. e Wilmington, North Carolina 28401-4733 •
TO: NC DENR/Division of Environmental Management
Water Quality Section
127 Cardinal Drive Extension
Wilmington, NC 28405-3845
RE: Applied Analytical Office Building Expansion
Stormwater Certification
Permit No. SW8 980308
Dated: April 30, 1998
New Hanover County
A&K Project No. 97230
Engineer's Certification
KIM
John R. Andrew, P.E.
r� Z e J. A. Kuske, P.E.
I J. Phillip Norris, P.E.
• Fax [phone] • www.andrewandkuske.com
State Stormwater Management Systems
!permit No SW8 980308
I, John S. Tunstall, P. E. , as a duly registered Professional Engineer in the State of
North Carolina, having been authorized to observe (periodically, meekly, full time) the construction of
the project, Applied Analytical Office Building Expansion (Project)
for Applied Analytical Industries, Inc. (Project Owner) hereby state that, to the best of my
abilities, due care and diligence were used in the observation of the project construction such that the
construction was observed to be built within substantial compliance and intent of the approved plans
and specifications.
Required Items to be checked for this certification to be considered complete are on page 2 of this form.
Noted deviations from approved plans and specifications:
Signature
Registration No.
M
19851
'%J5191IFFl0
�� s
1S I•: A t.
DateIk
S.

PE Certification Requirements:
1. The drainage area to the system contains approximately the permitted acreage.
2. The drainage area to the system contains no more than the permitted amount of built -
upon area.
3. All the built -upon area associated with the project is graded such that the runoff
drains to the system.
4. The outlet/bypass structure elevations are per the approved plan.
5. The outlet structure is located per the approved plans.
6. Trash rack is provided on the outlet/bypass structure.
7. All slopes are grassed with permanent vegetation.
8. Vegetated slopes are no steeper than 3:1.
9. The inlets are located per the approved plans and do not cause short-circuiting of the
system.
10. The permitted amounts of surface area and/or volume have been provided.
11. Required drawdown devices are correctly sized per the approved plans.
12. All required design depths are provided.
13. All required parts of the system are provided, such as vegetated shelf, and a
forebay.
14. The overall dimensions of the system, as shown on the approved plans, are provided.
97230-1-3D-01 swcert
cc: Building Inspector
2

Position Title: Vice President
Job Family: Pharmaceutical Development Laboratories
FLSA: Exempt
Billable: Yes
Position Summary:
The Vice President has overall operational, regulatory and financial and client -service
responsibility for all assigned Pharmaceutical Development Laboratories. Acts in a
leading role to develop the business, foster scientific excellence and position the
service at the forefront of industry scientific, regulatory and business trends. Provides
guidance for resolving complex problems. Maintains a high level of professional
expertise. Acts in a leading role in client interaction, regulatory and/or client audits.
Develops production and resource plans across different groups that meet production
goals in terms of safety, quality, productivity (output and cost). Works with finance
groups to construct budgets (revenues, cost basis, staffing levels, investments).
Manages key performance metrics. Ensures proper staff training. Ensures that
deliverables are met or expectations are proactively managed towards alternative
solutions. Develops and implements key strategic polices and procedures. Works on
complex problems in which analysis of situations or data requires an in-depth
evaluation of various factors. Exercises judgment within broadly defined practices
and policies in selecting methods, techniques and evaluation criteria for obtaining
results.
Key Job Responsibilities:
• Optimizes efficiency of the working environment of the group.
• Ensures training of the group is complete.
• Ensures adherence to personnel and equipment SOPS and other regulatory
requirements.
• Acts as the leader in formulating and implementing policies that meet current and
upcoming compliance and operational trends.
• Provides scientific direction in terms of staying abreast of the latest technologies
and solving complex technical issues; maintains expert knowledge of scientific
trends as well as regulatory requirements.
• Works with business development group and leads client services activities
• Has revenue and budget and profit accountability for the assigned areas;
implements procedures to improve profitability.
• Approves SON
• Reviews and approves study reports.
• Approves all financial expenditures at the site
• Has ultimate accountability for regulatory compliance and action taken as a result
of regulatory body or client audits.
• Has ultimate responsibility for promotion of a safe working environment and
compliance with local and national safety regulations
September 2009 1 of 4

Position Title: Vice President
Job Family: Pharmaceutical Development Laboratories
• Reviews /Approves financial reports to Executive management as necessary
• Promotes a productive work ethic.
• Demonstrates company loyalty in relations with Company personnel and clients.
• Accountable for developing, reviewing and meeting budget for business area.
Essential Job Requirements:
Education:
PhD with minimum 10+ years of related experience managing laboratories in a
pharmaceutical environment.
Must exhibit strong leadership and management skills and previous experience
managing people. Technical / scientific credentials must be complemented by
excellent project management skills (including expense control and timeline
management), a strategic and results -oriented approach to operational excellence,
proven ability to develop productive professional relationships, and sound operational
judgment.
Knowledge:
• Demonstrated knowledge and hands on experience in the area of responsibility.
• Excellent understanding of the theoretical background/fundamentals of the work.
• Outstanding capability of client management.
• Ability to plan and forecast the financial performance of the organization.
• Understands industry business trends.
• Understands regulatory and technical trends.
• Strong knowledge of financial metrics and budgets.
• Strong understanding of hiring and employment practices.
Required skills/Abilities:
• Strong problem solving capabilities.
• Consistent attention to details.
• Excellent time management skills.
• Good organizational skills.
• Excellent interpersonal communication skills.
• Excellent presentation skills.
• Ability to multi -task.
• Computer proficient.
• Strong work ethic.
• Able to effectively train others.
�+ Innovative technical problem solving skills.
• Strong Team Building and Management skills.
• Excellent leadership skills.
• Creative problem solving.
September 2009 2 of 4

Position Title: Vice President
Job Family: Pharmaceutical Development Laboratories
• Some travel required.
Supervision Received: General
Exercises independent judgment in developing methods, techniques and evaluation
criteria for obtaining results. Acts independently to determine methods and
procedures on new assignments. May seek management direction for problems of
diverse and/or complex scope.
Physical Demands:
The physical demands described here are representative of those that must be met by
an employee to successfully perform the essential functions of this job. Reasonable
accommodations may be made to enable individuals with disabilities to perform the
essential functions.
While performing the duties of this Job, the employee is regularly required to use
hands to finger, handle, or feel; reach with hands and arms; talk or hear and smell.
The employee is frequently required to sit. The employee is occasionally required to
stand; walk and stoop, kneel, crouch, or crawl. The employee must regularly lift
and/or move up to 10 pounds, frequently lift and/or move up to 25 pounds and
occasionally lift and/or move up to 50 pounds. Specific vision abilities required by
this job include close vision, distance vision, color vision, peripheral vision, depth
perception and ability to adjust focus.
Environment and Protective Equipment:
The work environment characteristics described here are representative of those an
employee encounters while performing the essential functions of this job. Reasonable
accommodations may be made to enable individuals with disabilities to perform the
essential functions.
While performing the duties of this Job, the employee is occasionally exposed to
moving mechanical parts and vibration. The noise level in the work environment is
usually very quiet.
LIMITATIONS AND DISCLAIMER
The above job description is meant to describe the general nature and level of work
being performed; it is not intended to be construed as an exhaustive list of all
responsibilities, duties, and skills required for the position.
All job requirements are subject to possible modification to reasonably accommodate
individuals with disabilities. Some requirements are may exclude individuals who
pose a direct threat or significant risk to the health and safety of themselves or other
employees.
September 2009 3 of 4

Position Title: Vice President
Job Family: Pharmaceutical Development Laboratories
This job description in no way states or implies that these are the only duties to be
performed by the employee occupying this position. Employees will be required to
follow job -related instructions and to perform other job -related duties requested by
their supervisor in compliance with Federal and State Laws.
Requirements are representative of minimum levels of knowledge, skills, and/or
abilities. To perform the job successfully, the employee must possess the abilities or
aptitudes to perform each duty proficiently.
September 2009 4 of 4