DEQ-CFW_00022441

From: Culpepper, Linda [/O=EXCHANGELABS/OU=EXCHANGE ADMINISTRATIVE GROUP
(FYDIBOHF23SPDLT)/CN=RECIPIENTS/CN=73D475CBAE324A29B87El7llDC9A79C5-LMCULPEPPER]
Sent: 7/12/2017 5:36:07 PM
To: Holman, Sheila [/o=ExchangeLabs/ou=Exchange Administrative Group
(FYDI BOHF23SPDLT)/cn=Recipients/cn=94a3f69674d34b769b3bd834a97105c5-schoI man]
Subject: Question - FW: DRAFT Risk Assessment FAQ
Question — is the relative source contribution for bottle-fed infants sub -population 100%. or 201/o9
Want me to respond back to DI -II -IS or are there other questions this needs to be rolled into?
3. Why did NCDHHS update its preliminary assessment?
Since sharing the initial health assessment, NC DHHS has continued to review all available health information
about GenX. Based on this review and continuing discussions and a more recent consensus with EPA, NC
DHHS has determined that sufficient data are available to update the initial assessment.
The current revised health screening level is 140 ng/L for the most vulnerable population- i.e. bottle-fed infants,
the population that drinks the largest volume of water per body weight. This revised health screening level is
lower than the level in the initial assessment for several reasons, including the following: First, after
consultation with EPA, a different set of animal studies was identified as an appropriate starting point for the
assessment. This change lowered the health screening level by 10-fold. Since the new starting point was based
on short-term rather than long-term (chronic) animal studies, an additional uncertainty factor was added, which
lowered the level by another I 0-fold. In addition, while the initial assessment assumed that drinking water was
the only source of exposure, the revised estimate includes an assumption that only 20% of a person's GenX
exposure comes from drinking water, lowering the level another 5-fold. This 20% is a generic assumption used
as a default by the EPA when information is lacking about other exposure routes; it was included based on
additional review and consultation with EPA. There is limited information available about actual sources of
exposure to GenX in the environment. Details of the specific updates and calculations for the revised health
screening level are presented in Appendix 3.
As with the initial preliminary assessment, it is important to note that this updated risk assessment is not final
and is likely to be revised as new information becomes available. Provisional screening levels for other
populations are presented in Appendix 4.
Linda Culpepper
Deputy Director
Division of Water Resources
North Carollna Departrnent of EnvironrnentaQuality
Mail Servlce Center
Phone[phone]
From: Shehee, Mina
Sent: Wednesday, July 12, 2017 12:24 PM
To: Moore, Zack <[e-mail]>; Benton, Mark <Mark. Benton @dhhs.nc.gov>; Holman, Sheila
<[e-mail]>; Culpepper, Linda <1 i nda.cu I pepper@ ncden r.gov>; Kritzer, Jamie
<jam ie. kritzer@ ncdenr.gov>
Cc: Mackey, Chris <Chris. Mackey@ dhhs. nc.gov>; Coleman, Scott <[e-mail]>; Staley, Danny
DEQ-CFW-00022441

<[e-mail]>
Subject: RE: DRAFT Risk Assessment FAQ
Changed level to goal (except drinking water equivalent levels) in appendices — see attached
Sent: Wednesday, July 12, 2017 12:01 PM
To: Benton, Mark <Mark.Benton dhhs.nc. ov>; Holman, Sheila <sheila.holman ncdenr. oy>; Culpepper, Linda
<[e-mail]>; Kritzer, Jamie <[e-mail]>
Cc: Mackey, Chris <[e-mail]>; Coleman, Scott <[e-mail]>; Shehee, Mina
<[e-mail]. ov>; Staley, Danny <Dann .Stale @dhhs.nc. ov>
Subject: RE: DRAFT Risk Assessement FAQ
Importance: High
Hi all,
We have attempted to incorporate feedback received so far in the attached version. Please circulate this to other state
partners who might need to review.
Our goal is to have this posted and have a press release ready to go as soon as the QA/QC process is completed. Any
feedback you can provide before then would he appreciated. Also, please let me know if there is a draft release from
DEQ that we could review to help move that part along. Thanks.
.Zack
Zack Moore, MD, MPH
State Epidemiologist and Epiderniology Section Chief
Division of Public Health
North Carolina Department of Health and Human Services
919 54-172 a office
919 733 0490 fax (secure)
zack.moore( dhhs.nc.00v
225 N. McDowell St.
Raleigh, NC 27603
1902 Mail Service Center
Raleigh, NC 27699-1902
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Twitter Yo uT€.€he
Unauthorized disclosure of juvenile, health, legally privileged, or othenAl€se confidential information, Including confidential Information relating to an ongoing State
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From: Benton, Mark
Sent: Tuesday, July 11, 2017 5:31 PM
DEQ-CFW 00022442

Cc: Mackey, Chris; Coleman, Scott; Moore, Zack
Subject: Fwd: DRAF-F Risk Assessement FAQ
Sent by Mirk "I'. Benton, Dcpat-y Secretary for Ficalth Services
NC Department of Health & Human Services
mark. benton(ii)',dhhs.nc.gov
-------- Original message --------
From: "Moore, Zack" <zack--rnoore((Tdhhs.nc.gov>
---------------------------- — --------
Date: 7/11/17 5:28 PM (GMT-05:00)
To: "Benton, Mark" <Mark. Benton0a.dhhs.nc._gov>, "Mackey, Chris" <Chris.MackeyLa)dhhs.nc.gov>,
"Coleman, Scott" <Scott.Coleman L-Whhs.nc.gov>, "Staley, Danny" <Danny.StaleyLa)dhhs.nc.&ov>
Cc: "Shehee, Mina" <mina.sheheeLa)dhhs.nc.gov>
Subject: DRAFT Risk Assessement FAQ
Hi all,
Here are the DRAFT FAQs regarding our initial and revised risk assessment. Please review and provide
feedback (Mina: I made some changes so please share with staff to make sure I didn't mess anything up). Please
also share this with DEQ and the Governor's Office when you feel it is appropriate. Thanks.
Zack
11 ^ II I I•, - I a I -i
North Carolina Department of Health and Human Services
4W—W �-• �-
919 733 0490 fax (secure)
[e-mail]
225 N. McDowell St.
DEQ-CFW-00022443

ZBMMSMU•!
1902 Mail Service Center
'a Re- abe
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Unauthorized disclosure of juvenile, health, legally privileged, or otherwise confidential information, including confidential information relating to an ongoing State
procurement effort, is prohibited by law. If you have received this e-mail in error, please notify the sender immediately and delete all records of this e-mail.
Email correspondence to and from this address is subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized State
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DEQ-CFW-00022444