DEQ-CFW_00072921

Per- and Polyfluoroalkyl Substances (PFAS)
Sampling studies and methods development for water and other environmental media
Background
Per- and polyfluoroalkyl substances (PFAS) are a large
group of manufactured compounds used in a variety of
industries, such as aerospace, automotive, textiles, and
electronics, and are used in some food packaging and
firefighting materials. For example, they may be used to
make products more resistant to stains, grease and
water. In the environment, some PFAS break down very
slowly, if at all, allowing bioaccumulation (concentration)
to occur in humans and wildlife. Some have been found
to be toxic to laboratory animals, producing
reproductive, developmental, and systemic effects in
laboratory tests.
The U.S. Environmental Protection Agency's (EPA)
methods for analyzing PFAS in environmental media are
in various stages of development. EPA is working to
develop robust analytical methods for groundwater,
surface water, wastewater, and solids, including soils,
sediments, and biosolids.
Drinking Water
Analysis using EPA Method 537
To assess for potential human exposure to PFAS in
drinking water, EPA -approved commercial drinking water
laboratories successfully analyzed finished (treated)
drinking water samples for six PFAS monitored under the
third Unregulated Contaminant Monitoring Rule
(UCMR3). For the UCMR3 analyses, laboratories used
EPA Method 537, which also includes eight additional
PFAS analytes not listed on the UCMR3.
Health Advisories
In May 2016, EPA issued drinking water health advisories
for two types of PFAS—perfluorooctanoic acid (PFOA)
and perfluorooctanesulfonic acid (PFOS). EPA's health
advisories are non -enforceable and non -regulatory, and
provide technical information to state agencies and
other public health officials on health effects, analytical
methodologies, and treatment technologies associated
with drinking water contamination.
EPA avpeets to have draft methods for
14,ater and solids by,fall 2017.
Method Development and Validation
Currently, there are no standard EPA methods for
analyzing PFAS in groundwater, surface water,
wastewater, or solids. Some U.S. laboratories are using
modified methods for non -drinking water samples
based on EPA Method 537. These modified methods
have no consistent sample collection guidelines and
have not been validated nor systematically assessed for
data quality.
To provide validated methods for sample types other
than drinking water, which will fill this sampling and
analytical gap, EPA formed a cross -Agency method
development and validation workgroup. The workgroup
will develop analytical methods for quantifying 24 PFAS
analytes. The method development process will occur in
a phased approach:
FEW M- EPA labs will test three existing analytical
protocols for preparing and analyzing 24 PFAS analytes
in surface water, groundwater, and wastewater.
Several external labs will validate the most
promising protocol(s) based on the Phase I results.
DEQ-CFW 00072921

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Studies on Sampling and Storage
EPA is currently running time -based studies on
degradation or loss of target analytes during sample
storage (45 days) and assessing the effects of different
sample vessel materials (e.g., plastic, glass) on analyte
recovery. EPA will also develop standard operating
procedures for field sampling, which are critical for
minimizing sample contamination and optimizing data
quality for site characterization.
Due to the widespread use of PFAS, many materials
normally used in field and laboratory operations contain
PFAS. For example, polytetrafluoroethylene products
(tubing, sample containers, and sampling tools) are often
used in sampling; however, since these products contain
PFAS, they cannot be used in sampling for PFAS. In
addition, many consumer goods, such as water-resistant
jackets or fast food wrappers, brought to a sampling site
may contain PFAS that can contaminate samples. Proper
field sampling and laboratory hygiene protocols are
critical to ensuring that testing results reflect actual PFAS
levels in the analyzed material.
Technical Contacts:
• Christopher Impellitteri
[e-mail]
• Schatzi Fitz -James
fitz-*[e-mail]
• Cynthia Caporale
[e-mail]
Communications Contact:
• Michelle Latham
[e-mail]
Additional EPA Information
DEQ-CFW 00072922

SO E RA FACT SHEET
United States PFOA & PFOS Drinking Water
Environmental Protection
Agency Health Advisories
N ` ; EPA has established health advisories for PFOA and PFOS based on the
s agency's assessment of the latest peer -reviewed science to provide drinking
fah
water system operators, and state, tribal and local officials who have the
primary responsibility for overseeing these systems, with information on
the health risks of these chemicals, so they can take the appropriate actions
i
to protect their residents. EPA is committed to sup
porting
= pp g states and public
water systems as they determine the appropriate steps to reduce exposure
to PFOA and PFOS in drinking water. As science on health effects of these
ichemicals evolves, EPA will continue to evaluate new evidence.
Background on PFOA and PFOS
PFOA and PFOS are fluorinated organic chemicals that are part of a larger
group of chemicals referred to as perfluoroalkyl substances (PFASs). PFOA
and PFOS have been the most extensively produced and studied of these
chemicals. They have been used to make carpets, clothing, fabrics'for furni-
ture, paper packaging for food and other materials (e.g., cookware) that are
resistant to water, grease or stains. They are also used for firefighting at air-
fields and in a number of industrial processes.
t
Because these chemicals have been used in an array of consumer products,
most people have been exposed to them. Between 2000 and 2002, PFOS
0
was voluntarily phased out of production in the U.S. by its primary manufac-
turer. In 2006, eight major companies voluntarily agreed to phase out their
-� global production of PFOA and PFOA-related chemicals, although there are a
limited number of ongoing uses. Scientists have found PFOA and PFOS in the
"x blood of nearly all the people they tested but these studies show that the
-:,w
N levels of PFOA and PFOS in blood have been decreasing. While consumer
products and food are a large source of exposure to these chemicals for
most people, drinking water can be an additional source in the small per-
centage of communities where these chemicals have contaminated water
supplies. Such contamination is typically localized and associated with a spe-
cific facility, for example, an industrial facility where these chemicals were
produced or used to manufacture other products or an airfield at which they
were used for firefighting.
EPA develops health advisories to provide information on contaminants that can cause human health effects
and are known or anticipated to occur.in drinking water. EPA's health advisories are non -enforceable and
non -regulatory and provide technical information to states agencies and other public health officials on
health effects, analytical`methodologies, and treatment technologies associated with drinking water contam-
ination. In 2009, EPA published provisional health advisories for PFOA and PFOS based on the evidence avail-
able at that time. The science has evolved since then and EPA is now replacing the 2009 provisional adviso-
ries with new, lifetime health advisories.
US Environmental Protection Agency
November2016 EPA800-F-16-003
DEQ-CFW 00072923

FACT SHEET
PFOA & PFOS Drinking Water Health Advisories
To provide Americans, including the most sensitive populations, with a margin of protection from a life-
time of exposure to PFOA and PFOS from drinking water, EPA established the health advisory levels at 70
parts per trillion. When both PFOA and PFOS are found in drinking water, the combined concentrations
of PFOA and PFOS should be compared with the 70 parts per trillion health advisory level. This health advi-
sory level offers a margin of protection for all Americans throughout their life from adverse health effects
resulting from exposure to PFOA and PFOS in drinking water.
How the Health Advisories were developed
EPA's health advisories are based on the best available peer -reviewed studies of the effects of PFOA and
PFOS on laboratory animals (rats and mice) and were also informed by epidemiological studies of human
populations that have been exposed to PFASs. These studies indicate that exposure to PFOA and PFOS over
certain levels may result in adverse health effects, including developmental effects to fetuses during preg-
nancy or to breastfed infants (e.g., low birth weight, accelerated puberty, skeletal variations), cancer (e.g.,
testicular, kidney), liver effects (e.g., tissue damage), immune effects (e.g., antibody production and im-
munity), thyroid effects and other effects (e.g., cholesterol changes).
EPA's health advisory levels were calculated to offer a margin of protection against adverse health effects
to the most sensitive populations: fetuses during pregnancy and breastfed infants. The health advisory lev-
els are calculated based on the drinking water intake of lactating women, who drink more water than other
people and can pass these chemicals along to nursing infants through breastmilk.
Steps to Assess Contamination
If water sampling results confirm that drinking water contains PFOA and PFOS at individual or combined
concentrations greater than 70 parts per trillion, water systems should quickly undertake additional sam-
pling to assess the level, scope and localized source of contamination to inform next steps
Steps to Inform
If water sampling results confirm that drinking water contains PFOA and PFOS at individual or combined
concentrations greater than 70 parts per trillion, water systems should promptly notify their State drinking
water safety agency (or with EPA in jurisdictions for which EPA is the primary drinking water safety agency)
and consult with the relevant agency on the best approach to conduct additional sampling.
Drinking water systems and public health officials should also promptly provide consumers with infor-
mation about the levels of PFOA and PFOS in their drinking water. This notice should include specific infor-
mation on the risks to fetuses during pregnancy and breastfed and formula -fed infants from exposure to"
drinking water with an individual or combined concentration of PFOA-and PFOS above EPA's health adviso-
ry level of 70 parts per trillion. In addition, the notification should include actions they are taking and identi-
fy options that consumers may consider to reduce risk such as seeking an alternative drinking water source,
or in the case of parents of formula -fed infants, using formula that does not require adding water.
US Environmental Protection Agency
November 2016 EPA 800-F-16-003
DEQ-CFW 00072924

FACT SHEET
PFOA & PFOS Drinking Water Health Advisories
Steps to Limit Exposure
A number of options are available to drinking water systems to lower concentrations of PFOA and PFOS in
their drinking water supply. In some cases, drinking water systems can reduce concentrations of perfluo-
roalkyl substances, including PFOA and PFOS, by closing contaminated wells or changing rates of blending
of water sources. Alternatively, public water systems can treat source water with activated carbon or high
pressure membrane systems (e.g., reverse osmosis) to remove PFOA and PFOS from drinking water. These
treatment systems are used by some public water systems today, but should be carefully designed and
maintained to ensure that they are effective for treating PFOA and PFOS. In some communities, entities
have provided bottled water to consumers while steps to reduce or remove PFOA or PFOS from drinking
water or to establish a new water supply are completed.
Vlany home drinking water treatment units are certified by independent accredited third party organizations
against American National Standards Institute (ANSI) standards to verify their contaminant removal claims.
JSF International (NSF®) has developed a protocol for NSF/ANSI Standards 53 and 58 that establishes
ninimum requirements for materials, design and construction, and performance of point -of -use (POU)
activated carbon drinking water treatment systems and reverse osmosis systems that are designed to reduce
'FOA and PFOS in public water supplies. The protocol has been established to certify systems (e.g., home
reatment systems) that meet the minimum requirements. The systems are evaluated for contaminant
eduction by challenging them with an influent of 1.5±30% µg/L (total of both PFOA and PFOS) and must
educe this concentration by more than 95% to 0.07 µg/L or less (total of both PFOA and PFOS) throughout
he manufacturer's stated life of the treatment system. Product certification to this protocol for testing home
reatment systems verifies that devices effectively reduces PFOA and PFOS to acceptable levels.
Between 2000 and 2002, PFOS was voluntarily phased out of production in the U.S. by its primary manufac-
turer, 3M. EPA also issued regulations to limit future manufacturing, including importation, of PFOS and its
precursors, without first having EPA review the new use. A limited set of existing uses for PFOS (fire re-
sistant aviation hydraulic fluids, photography and film products, photomicrolithography process to produce
semiconductors, metal finishing and plating baths, component of an etchant) was excluded from these reg-
ulations because these uses were ongoing and alternatives were not available.
In 2006, EPA asked eight major companies to commit to working toward the elimination of their production
and use of PFOA, and chemicals that degrade to PFOA, from emissions and products by the end of 2015. All
eight companies have indicated that they have phased out PFOA, and chemicals that degrade to PFOA,
from emissions and products by the end of 2015. Additionally, PFOA is included in EPA's proposed Toxic
Substance Control'Act's Significant New Use Rule (SNUB) issued in January 2015 which will ensure that EPA
has an opportunity to review any efforts to reintroduce the chemical into the marketplace and take action,
as necessary, to address potential concerns.
US Environmental Protection Agency
November 2016 EPA 800-F-16-003
DEQ-CFW 00072925

FACT SHEET
PFOA & PFOS Drinking Water Health Advisories
EPA has not established national primary drinking water regulations for PFOA and PFOS. EPA is evaluating
PFOA and PFOS as drinking water contaminants in accordance with the process required. by the Safe Drink-
ing Water Act (SDWA). To regulate a contaminant under SDWA, EPA must find that it: (1) may have adverse
health effects; (2) occurs frequently (or there is a substantial likelihood that it occurs frequently) at levels of
public health concern; and (3) there is a meaningful opportunity for health risk reduction for people served
by public water systems.
EPA included PFOA and PFOS among the list of contaminants that water systems are required to monitor
under the third Unregulated Contaminant Monitoring Rule (UCMR 3) in 2012. Results of this monitoring
effort are updated regularly and can be found on the publicly -available National Contaminant Occurrence
Database (NCOD) (https://www.epa.gov/dwucmr/occurrence-data-unregulated-contaminant-monitoring
rule#3). In accordance with SDWA, EPA will consider the occurrence data from UCMR 3, along with the peer
reviewed health effects assessments supporting the PFOA and PFOS Health Advisories, to make a reg-
ulatory determination on whether to initiate the process to develop a national primary drinking water regu-
lation.
In addition, EPA plans to begin a separate effort to determine the range of PFAS for which an Integrated Risk
Information System (IRIS) assessment is needed. The IRIS Program identifies and characterizes the health
hazards of chemicals found in the environment. IRIS assessments inform the first two steps of the risk
assessment process: hazard identification, and dose-response..As indicated in the 2015 IRIS Multi -Year
Agenda, the IRIS Program will be working with other EPA offices to determine the range of PFAS com-
pounds and the scope of assessment required to best meet Agency needs. More about this effort can be
found at https://www.epa.goy/iris/iris-agenda.
!se health advisories only apply to exposure scenarios involving drinking water. They are not appropriate
use, in identifying risk levels for ingestion of food sources, including: fish, meat produced from livestock
t consumes contaminated water, or crops irrigated with contaminated water.
he health advisories are based on exposure from drinking water ingestion, not from skin contact or breathing.
he advisory values are calculated based on drinking water consumption and household use of drinking water
uring food preparation (e.g., cooking or to prepare coffee, tea or soup). To develop the advisories, EPA
insidered non -drinking water sources of exposure to PFOA and PFOS, including: air, food, dust, and consumer
roducts. In January 2016 the Food and Drug Administration amended its regulations to no longer allow PFOA
nd PFOS to be added in food packaging, which will likely decrease one source of non -drinking water exposure.
US Environmental Protection Agency 4 November 2016 EPA 800-F-16-003
DEQ-CFW 00072926

• EPA's Drinking Water Health Advisories for PFOA and PFOS can be found at: https://www.epa.gov/
grou nd-water-and-drinking-water/d rin king-water-health-advisories-pfoa-and-pfos
• PFOA and PFOS data collected under EPA's Unregulated Contaminant Monitoring Rule are available:
https://www.epa.gov/dwucmr/occurrence-data-unregulated-con taminant-monitoring-rule
• EPA's stewardship program for PFAS related to TSCA: https://www.epa.goy/assessing-and-managing-
chemicals-under-tsca/and-polyfluoroalkyl-substances-pfass-under-tsca
• EPA's research activities on PFASs can be found at: http://www.epa.gov/chemical-research/­­
P erfluor in ated -chemical -Pfc-re search
• The Agency for Toxic Substances and Disease Registry's Perflourinated Chemicals and Your Health
webpage at: http://www.atsdr.cdc.gov/PFC/
low
E PA
United Mates
Environmental Protection
Agency
US Environmental Protection Agency
November2016 EPA800-F-16-003
DEQ-CFW 00072927