DEQ-CFW_00078299

GenX (2,3,3,3 -tetrafluoro-2-(heptafluoropropoxy)propionic acid, ammonium salt,
CAS# 62037-80-3)
What is GenX?
GenX is a chemical used in the manufacturing of fluoropolymer resins, which are used for
nonstick coatings and other purposes. GenX is part of the fluorinated family of compounds that
includes the chemicals PFOS and PFOA. In response to concerns about environmental and
human health effects of PFOA, GenX was developed as a replacement product.
Has the state or federal government made recommendations to protecthuman health?
U.S. EPA has published health advisory levels for PF:OA/:PFOS:,::W::hich are in theSbme family of
chemicals as GenX2 . However, these1evels should not::be used for evaluating the health risks of
GenX due to differences in chemical stru : ctu::re::that can affect::how the chemical interacts with
the body.
How can GenX affedyny health::?::::
Limited health information isavailable for GenX. PFOA and PFOS (chemicals that are part of the
same family of fluorinated:::combounds) were recently reviewed by the EPA. The most common
effects observed in laboratory tests were kidney and testicular cancer, impaired fetal
development, and effects on the liver, thyroid, and immune system. It is expected that
exposure to sufficient amounts of GenX or other related chemicals might cause some or all of
these health effects. However, current data suggest that these effects are unlikely at the levels
detected in the Cape Fear River during 2013-2014. If you are concerned about exposure to
GenX and your health, please begin by speaking with your medical provider.
Revised June 14, 2017
DEQ-CFW-00078299

z. Sun etal. Legacy and Emerging perfluuma|hyl Substances Are Important Drinking Water Contaminants inthe Cape Fear River
Watershed ofNorth Carolina. Environmental Science & Technology Letters. Nov znza oo|:zuzu21/ao.estleuabousyo.
z. USEPA. Drinking Water Health Advisories for PFOA and PFOS. https://www.epa.gov/ground-water-and-drinking-water/drinking-
water-health-advisories-pfoa-and-pfos
s. ECHA Toxicological Summary for Ammonium 2,3,3,3-Tetrafluoro-2-(Heptafluoropropoxy)Propanoate.
https://echa.eurupa.eu/registration'dossier/-/,egiste,ed'dnoier/za7y/7/1
«. Beekman, M. et.al. 2016. Evaluation of substances used in the GenX technology by Chemours, Dordrecht. RIVIM Letter Report:
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Revised June 14, 2017